News National Institute of Health to Fund Preclinical Development of Trethera Lead Drug, TRE-515, for Treatment of Crohn’s Disease Globally Recognized Expert in Rare Neurologic Diseases, Dr. Michael Levy, Joins Trethera Scientific Advisory Board Trethera Receives NIH Grant for Preclinical Development in the Pediatric Neurologic Disease Acute Disseminated Encephalomyelitis Trethera Announces Invited Speaker Presentations at the Purine and Pyrimidine Society Symposium and General Assembly Trethera Receives Grant from National Institute of Allergy and Infectious Diseases for the Advancement of TRE-515 in Lupus Dose Escalation Portion of Phase 1 Solid Tumors Trial Produces Favorable Results in Heavily Pretreated Solid Tumor Patients Trethera Announces Appointment of Laurent Dubois to Board of Directors Trethera Announces Poster Presentation at the Americas Committee for Treatment and Research in Multiple Sclerosis Annual Meeting Trethera Announces Appointment of R. Boyd Quinnell to Board of Directors Trethera Receives $1.6 Million National Eye Institute Grant for Continued Advancement of TRE-515 Optic Neuritis Program Trethera Announces Multiple Sclerosis Treatment Poster Presentation at the American Neurological Association Annual Meeting U.S. Patent Office Issues Trethera Composition of Matter Patent Covering TRE-515, Extending Market Exclusivity to Late 2041 Trethera and UCLA Publish Data Demonstrating TRE-515 Ability to Control and Improve Multiple Sclerosis Symptoms in Mouse Models Trethera Receives U.S. Patent Office Notice of Allowance Covering TRE-515 Structural Claims, Extending Protections to Late 2041 Trethera Phase 1 Solid Tumors Trial Dose Escalates To Fourth Cohort After Safety Review Committee Determines Primary Trial Endpoint Achieved Trethera Scientific Founder Dr. Caius Radu To Present Research At Los Angeles Bioscience Ecosystem Summit 2022 Trethera Announces Completion of $3.8 Million Seed Funding Round From Current Investors Trethera Announces Prostate Cancer Poster Presentation at the American Association for Cancer Research Annual Meeting Safety Review Committee Advances Trethera Phase 1 Solid Tumors Trial to Next Dose After First Patient Cohort Achieves Primary Endpoint Trethera Announces FDA Orphan Drug Designation Granted to TRE-515 for the Treatment of Demyelinating Optic Neuritis Trethera Doses First Patient in Landmark Clinical Trial for the Treatment of Solid Tumors With First-In-Class Drug TRE-515 Globally Recognized Multiple Sclerosis Expert, Dr. Lawrence “Larry” Steinman, Joins Trethera Scientific Advisory Board Trethera Receives FDA Approval To Initiate TRE-515 Phase 1 Clinical Trial in Solid Tumors Monotherapy Trethera Announces Jefferies & Company Chairman Emeritus Frank Baxter as Special Advisor Trethera Announces Completion of $3.2 Million Seed Funding Round From Current Investors Trethera Announces FDA Orphan Drug Designation Granted to TRE-515 in the Treatment of Acute Disseminated Encephalomyelitis View AllPublications ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress. View All
